Alan did his Ph.D. at the University of Cambridge with Tom Blundell and was a postdoc for Matt Higgins and Venki Ramakrishnan. He started at HMS in September 2017 and was named a Pew Scholar in 2019.
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People
Jacob R. Anderson
Ph.D. Candidate
Jacob received his bachelor's degree from the University of Michigan in 2017. He is a Chemical Biology student in Harvard's MD-PhD program. Before graduate school, Jacob worked in Nils Walter's laboratory using TIRF microscopy to measure kinetics of oligonucleotide binding and in Adriaan Bax's laboratory measuring rates of hydrogen exchange of backbone amides in intrinsically disordered proteins. Jacob joined the lab in May 2020.
Jin Dai
Post-Doctoral Fellow
Jin Dai joined the lab in August 2021 and was the first member to join from another cilia lab. Jin obtained his B.Sc. from Peking University, Beijing, before moving to the U.S. for a Ph.D. with Dr. Karl Lechtreck. In his research with Karl, Jin studied how axonemal dyneins are transported by intraflagellar transport.
Miao Gui
Post-Doctoral Fellow
Miao trained at Peking University and Tsinghua University as a joint Ph.D. He then joined the Innovation Center for Structural Biology of Tsinghua University as a postdoc. In China, Miao mainly worked on the virus surface glycoproteins using cryo-EM. Miao joined the lab in January 2019 and was awarded a BCMP-Merck Postdoctoral Fellowship later that year. He studies the mechanoregulation of ciliary motility and recently determined the structure of a radial spoke. Miao also collaborates with the Wagner lab to determine cryo-EM structures of nanodisc-embedded GPCR complexes. Miao is a 2021 Charles A King Trust Postdoctoral Fellow.
Shimi Meleppattu
Research associate
Shimi received her Ph.D. degree from the Department of Biotechnology, Pune University, India where she studied stress-induced regulation of protein synthesis in protozoan parasites. As a postdoctoral fellow at Ben-Gurion University, Israel, and later at Harvard Medical School, she worked on the characterization of translational initiation complexes in Leishmania. Shimi joined the lab in 2019 as a Research Associate.
Sandeep Singh
Post-Doctoral Fellow
Sandeep received his Ph.D. degree from IMTECH, India in biochemistry and molecular biology. He studied the nitric oxide evasion strategy of Mycobacterium tuberculosis. Later, he joined Purdue University as a postdoc and worked on transmembrane signaling and the formation of membrane-protein supercomplexes. Sandeep currently works on the structure and function of complexes involved in transporting membrane proteins including the mammalian BBSome.
Travis Walton
Post-Doctoral Fellow
Travis received his PhD from Harvard University in 2019 by uncovering a novel chemical mechanism for nonenzymatic RNA polymerization in the laboratory of Jack W. Szostak. Before his doctoral training, he studied transcriptional regulation during C. elegans development using microscopic and genomic approaches in the laboratory of John I. Murray at the University of Pennsylvania. Travis is continuing his scientific training in the Brown lab with biochemical and structural studies of axonemal dyneins. Travis is a 2019 Helen Hay Whitney Fellow.
Haixia Zhou
Post-Doctoral Fellow
Haixia received her Ph.D. from Tsinghua University in 2019. She worked on isolating and characterizing new monoclonal antibodies against the MERS-CoV infection by combining cryo-EM, X-ray crystallography, and biochemistry. Haixia joined the lab in September 2019 as a joint postdoc with Dr. Johannes Walter. Haixia is a 2021 BCMP-Merck Postdoctoral Fellow.