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Structural specializations of the sperm tail 
Leung MR, Zeng J, Wang X, Roelofs MC, Huang W, Chiozzi RZ, Hevler JF, Heck AJR, Dutcher SK, Brown A, Zhang R, Zeev-Ben-Mordehai Z 


Axonemal structures reveal mechanoregulatory and disease mechanisms 
Walton T, Gui M, Velkova S, Fassad MR, Hirst RA, Haarman E, O'Callaghan C, Bottier M, Burgoyne T, Mitchison HM, Brown A 


Automated model building and protein identification in cryo-EM maps 
Jamali K, Kall L, Zhang R, Brown A, Kimanius D, Scheres S 


Ciliary radial spokes 
Brown A, Alford LM, Yang P 
The Chlamydomonas Sourcebook Volume 3: Cell Motility and Behavior, 3rd Edition


Mechanism of IFT-A polymerization into trains for ciliary transport 
Meleppattu S, Zhou H, Dai J, Gui M, Brown A 
Cell; 185: 4986–4998


TUBB4B variants specifically impact ciliary function, causing a ciliopathic spectrum 
Mechaussier S, et al 


Didemnin B and ternatin-4 inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes 
Juette MF, Carelli JD, Rundlet EJ, Brown A, Shao S, Ferguson A, Wasserman MR, Holm M, Taunton J, Blanchard SC 
eLife; 11: e81608


SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules 
Gui M, Croft JT, Zabeo D, Acharya V, Kollman JM, Burgoyne T, Höög JL, Brown A 
Proc. Natl. Acad. Sci. USA; 119(41): e2207605119


Modern and future methods for studying macromolecular assemblies in action 
Brown A, Fraternali F 
Curr. Opin. Struct. Biol.; 75: i102438


Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange 
Anderson JR, Li J, Springer TA, Brown A 
Blood; 140(12): 1419-1430


Ciliary central apparatus structure reveals mechanisms of microtubule patterning 
Gui M, Wang X, Dutcher SK, Brown A, Zhang R 
Nat. Struct. Mol. Biol.; 29: 483–492


Structure of CRL2Lrr1, the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates 
Zhou H, Zaher MS, Walter JC, Brown A 
Nucleic Acids Res.; 49: 13194-13206


De novo identification of mammalian ciliary motility proteins using cryo-EM 
Gui M, Farley H, Anujan P, Anderson JR, Maxwell DW, Whitchurch JB, Botsch JJ, Qui T, Meleppattu S, Singh SK, Zhang Q, Thompson J, Lucas JS, Bingle CD, Norris DP, Roy S, Brown A 
Cell; 184: 5791–5806


Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins 
Wang X, Fu Y, Beatty WL, Ma M, Brown A, Sibley LD, Zhang R 
Nat. Commun.; 12: 3065


Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs 
Zhang M, Gui M, Wang Z-F, Gorgulla C, Yu JJ, Wu H, Sun Z-Y, Klenk C, Merklinger L, Morstein L, Hagn F, Plückthun A, Brown A, Nasr ML, Wagner G 
Nat. Struct. Mol. Biol.; 28: 258–267


Structure of a microtubule-bound axonemal dynein 
Walton T, Wu H, Brown A. 
Nat. Commun.; 12: 477


Structures of radial spokes and associated complexes important for ciliary motility 
Gui M, Ma M, Sze-Tu E, Wang X, Koh F, Zhong ED, Berger B, Davis JH, Dutcher SK, Zhang R, Brown A. 
Nat. Struct. Mol. Biol.; 28: 29–37


Primary cilia: a closer look at the antenna of cells 
Brown A, Zhang R. 
Curr. Biol.; 30(24): PR1494-96


Structure and activation mechanism of the BBSome membrane protein trafficking complex 
Singh SK, Gui M, Koh F, Yip MCJ, Brown A 
eLife; 9:e53322


Mechanism of ribosome stalling during translation of a poly(A) tail 
Chandrasekaran V, Juszkiewicz S, Choi J, Puglisi JD, Brown A, Shao S, Ramakrishnan V, Hegde RS 
Nat. Struct. Mol. Biol.; 26:1132–1140


Structure of the decorated ciliary doublet microtubule 
Ma M, Stoyanova M, Rademacher G, Dutcher SK, Brown A, Zhang R 
Cell; 179(4): 909-922


Structural patching fosters divergence of mitochondrial ribosomes 
Petrov A, Wood EC, Bernier CR, Norris AM, Brown A, Amunts A 
Mol. Biol. Evol.; 36(2):207–219


Tiny crystals have big potential for determining structures of small molecules  
Brown A, Clardy J 
Nature; 564:348-349


Structures of translationally inactive mammalian ribosomes 
Brown A, Baird MR, Yip MCJ, Murray J, Shao S 
eLife; 7:e40486


Ribosomes and cryo-EM: a duet 
Brown A and Shao S 
Curr. Opin. Struct. Biol.; 52:1-7.


Structures of the human mitochondrial ribosome in native states of assembly 
Brown A, Rathore S, Kimanius D, Aibara S, Bai X-C, Rorbach J, Amunts A, Ramakrishnan V 
Nat. Struct. Mol. Biol.; 24, 866–869.


Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis 
Wong W, Bai X-C, Sleebs BE, Triglia T, Brown A, Thompson JK, Jackson KE, Hanssen E, Marapana DS, Fernandez IS, Ralph SA, Cowman AF, Scheres SHW, Baum J 
Nat. Microbiol.; 13;2:17031. 


The structure of the yeast mitochondrial ribosome 
Desai N, Brown A, Amunts A, Ramakrishnan V 
Science; 355(6324):528-531. 


Translational termination without a stop codon 
James NR, Brown A, Gordiyenko Y, Ramakrishnan V 
Science; 354(6318):1437-1440.


Decoding mammalian ribosome-mRNA states by translational GTPase complexes 
Shao S*, Murray J*, Brown A*, Taunton J, Ramakrishnan V, Hegde RS 
Cell; 167(5):1229-1240.


Ribosome-dependent activation of stringent control 
Brown A*, Fernández IS*, Gordiyenko Y, Ramakrishnan V 
Nature; 534(7606):277-80.


Organisation and regulation of mitochondrial protein synthesis. 
Ott M, Amunts A, Brown A 
Annu. Rev. Biochem.; 85:77-101.


Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding 
Lennartz F, Bengtsson A, Olsen RW, Joergensen L, Brown A, Remy L, Man P, Forest E, Barfod LK, Adams Y, Higgins MK, Jensen ATR 
J. Immunol.; 195(7):3273-3283.


Structural basis for stop codon recognition in eukaryotes 
Brown A*, Shao S*, Murray J, Hegde RS, Ramakrishnan V 
Nature; 524(7566):493-496.


Mechanistic origin of microtubule dynamic instability and its modulation by EB proteins 
Zhang R, Alushin GM, Brown A, Nogales E 
Cell; 162(4):849-859.


The structure of the human mitochondrial ribosome. 
Amunts A*, Brown A*, Toots J, Scheres SHW, Ramakrishnan V 
Science; 348(6230):95-98.


Structure and assembly pathway of the ribosome quality control complex 
Shao S, Brown A, Santhanam B, Hegde RS 
Mol. Cell; 57(3): 433-444.


Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions 
Brown A, Long F, Nicholls RA, Toots J, Emsley P, Murshudov G 
Acta Cryst. D71; 136-153.


Structure of the large ribosomal subunit from human mitochondria 
Brown A*, Amunts A*, Bai X-C, Sugimoto Y, Edwards PC, Murshudov G, Scheres SHW, Ramakrishnan V 
Science; 346(6210):718-722.


Structure of the malaria parasite 80S ribosome bound to the anti-protozoan drug emetine 
Wong W*, Bai X-C*, Brown A*, Fernández IS, Hanssen E, Condron M, Tan YH, Baum J, Scheres SHW 
eLife; 3:e03080.


Structure of the yeast mitochondrial large ribosomal subunit 
Amunts A*, Brown A*, Bai X-C*, Llacer JL*, Hussain T, Emsley P, Long F, Murshudov G, Scheres SHW, Ramakrishnan V 
Science; 343(6178):1485-1489.


The crystal structure of fibroblast growth factor 18 
Brown A, Adam LE, Blundell TL 
Protein Cell; 5(5):343-7.


From (+)-epigallocatechin gallate to a simplified synthetic analogue as a cytoadherence inhibitor for P. falciparum 
Gemma S, Brogi S, Patil PR, Giovani S, Lamponi S, Cappelli A, Novellino E, Brown A, Higgins MK, Mustafa K, Szestak T, Craig AG, Campiani G, Butini S, Brindisi M 
RCS Advances; 4, 4769-4781.


Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signalling 
Herbert C, Schieborr U, Saxena K, Juraszek J, de Smet F, Alcouffe C, Bianciotto M, Saladino G, Sibrac D, Kudlinzki D, Sreeramulu S, Brown A, Rigon P, Herault J-P, Lassalle G, Blundell TL, Rousseau F, Gils A, Schymkowitz J, Tompa P, Herbert JM, Carmeliet P, Gervasio FL, Schwalbe H, Bono F 
Cancer Cell; 23(4):489-501.


Cooperative heparin-mediated oligomerization of fibroblast growth factor-1 (FGF1) precedes recruitment of FGFR2 to ternary complexes. 
Brown A, Robinson CJ, Gallagher JT, Blundell TL 
Biophys. J.; 104(8):1720-1730.


Molecular architecture of a complex between an adhesion protein from the malaria parasite and intracellular adhesion molecule 1 
Brown A, Turner L, Christoffersen S, Zhao Y, Szestak T, Craig AG, Higgins MK 
J. Biol. Chem.; 288(8):5992-6003.


Structure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunity 
Higgins MK, Tkachenko O, Brown A, Reed J, Carrington M 
Proc. Natl. Acad. Sci. USA; 110(5):1905-10.


A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies 
Bengtsson A, Joergensen L, Rask TS, Olsen RW, Andersen MA, Turner L, Theander TG, Hviid L, Higgins MK, Craig A, Brown A, Jensen AT 
J. Immunol.; 190(1):240-9.


Carbohydrate binding molecules in malaria pathology 
Brown A, Higgins MK 
Curr. Opin. Struct. Biol.; 20(5):560-6.


Structural interactomics: informatics approaches to aid the interpretation of genetic variation and the development of novel therapeutics 
Lee S*, Brown A*, Pitt WR*, Higueruelo A, Bickerton GR, Gong S, Schreyer A, Tanramluk D, Blundell TL 
Mol. Biosyst.; 5(12):1456-72.


Analysis of cooperativity by Isothermal Titration Calorimetry 
Brown A 
IJMS; 10(8):3457-77.